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Image Search Results
Journal: Frontiers in Pharmacology
Article Title: Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling
doi: 10.3389/fphar.2021.693906
Figure Lengend Snippet: The impact of KX-01 on pulmonary protein expression. (A, B) : The expression of HIF-1α, p-Src; (C, D) : p-STAT3, STAT3 and p-STAT3/STAT3 was analyzed. BLM: bleomycin. Data are means ± SD ( n = 3). # p < 0.01 vs. sham; * p < 0.01 vs. BLM. Data were compared via ANOVAs with Dunnett’s test.
Article Snippet: The
Techniques: Expressing
Journal: Frontiers in Pharmacology
Article Title: Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling
doi: 10.3389/fphar.2021.693906
Figure Lengend Snippet: The impact of KX-01 on pulmonary α-SMA and p-STAT3 immunohistochemical staining. (A) and (4C) : Immunohistochemical staining was used to assess pulmonary α-SMA; (B–D) : Immunohistochemical staining was used to assess pulmonary p-STAT3 expression following BLM treatment with or without KX-01 administration. BLM: bleomycin. Data are means ± SD. # p < 0.01 vs. sham; * p < 0.01 vs. BLM. Data were compared via ANOVAs with Dunnett’s test.
Article Snippet: The
Techniques: Immunohistochemical staining, Staining, Expressing
Journal: Frontiers in Pharmacology
Article Title: Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling
doi: 10.3389/fphar.2021.693906
Figure Lengend Snippet: The impact of KX-01 on L929 cell proliferation and protein expression. (A) An EdU incorporation assay was used to assess L929 cell proliferation following CoCl 2 treatment with or without KX-01 for 72 h. (B–C) : The expression of α-SMA, collagen I, and collagen III were assessed; (D, E) : The expression of HIF-1α, p-Src (D–E); (F, G) : The expression of p-STAT3 and STAT3, and the ratio of p-STAT3/STAT3 was assessed. Data are means ± SD ( n = 3). # p < 0.01 vs. control; * p < 0.01 vs. CoCl 2 . Data were compared via ANOVAs with Dunnett's tst.
Article Snippet: The
Techniques: Expressing, Control
Journal: Frontiers in Pharmacology
Article Title: Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling
doi: 10.3389/fphar.2021.693906
Figure Lengend Snippet: The impact of KX-01 on L929 cell proliferation and protein expression in the presence of Roxadustat. (A) An EdU incorporation assay was used to assess L929 cell proliferation following CoCl 2 treatment with or without KX-01 or ROT for 72 h. (B, C) : The expression of α-SMA, collagen I, and collagen III were assessed; (D, E) : The expression of HIF-1α, p-Src, p-STAT3 and STAT3, and the ratio of p-STAT3/STAT3 were assessed. ROT: Roxadustat. Data are means ± SD ( n = 3). # p < 0.05, ## p < 0.01 vs. control; * p < 0.05, ** p < 0.01 vs. CoCl 2 . Data were compared via ANOVAs with Dunnett's test.
Article Snippet: The
Techniques: Expressing, Control
Journal: Frontiers in Pharmacology
Article Title: Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling
doi: 10.3389/fphar.2021.693906
Figure Lengend Snippet: The impact of KX-01 on L929 cell proliferation and protein expression in the presence of Stattic. (A) An EdU incorporation assay was used to assess L929 cell proliferation following CoCl 2 treatment with or without KX-01 or Stattic for 72 h. (B, C) : The expression of α-SMA, collagen I, and collagen III were assessed; (D, E) : The expression of HIF-1α, p-Src, p-STAT3 and STAT3, and the ratio of p-STAT3/STAT3 were assessed. Data are means ± SD ( n = 3). # p < 0.01 vs. control; * p < 0.05, ** p < 0.01 vs. CoCl 2 . Data were compared via ANOVAs with Dunnett's test.
Article Snippet: The
Techniques: Expressing, Control